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Other causes include diabetes; heart disease; cancer surgery of the prostate, bladder, colon or rectum; high blood pressure medications or antidepressants; a spinal injury; and a hormone imbalance, usually low testosterone, Lipshultz explained.
What are the side effects of sildenafil (Viagra)?
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Mydlo echoed that advice, adding, "Stop smoking, drink in moderation, lose weight, and maintain good blood pressure."
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Of the 99 men reviewed, the optimal dose for achieving erection satisfactory for sexual intercourse was: 25 mg – 6 (6.1%), 50 mg – 44 (44.4%), 75 mg – 1 (1%) and 100 mg – 38 (38.4%). The side effects most commonly encountered were headache (24%), flushing (16%), dyspepsia (12%), nasal congestion (10%), abnormal vision (5%), thirst (2%) and dazed feeling (2%). Uncommon side effects included palpitations (1), dizziness (1) and penile pain (1). Severe side effects necessitated withdrawal of Viagra in 2 patients (1 was a 'success' and the other a 'failure'). Out of 53 men who reported lack of side effects at Visit 2, 6 developed some side effects at Visit 3. Conversely, 11 men who had side effects at Visit 2 reported lack of them at Visit 3. There were no changes in the side effect profile between Visit 3 and Visit 4. Four men with Peyronie's disease had used sildenafil – two reported success with therapy while the other two failed. There were 2 isolated reports of prolonged erection (lasting 20 – 30 minutes) that were painless, which did not recur. There were no serious adverse events or deaths recorded during the trial period.
The findings are published in this weeks issue of the Proceedings of the National Academy of Sciences.
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Erectile Dysfunction Article
Call your doctor if you experience severe forms of these symptoms or if they do not go away after 4-8 hours.
ED, or erectile dysfunction, is medically defined as the inability to achieve or sustain an erection long enough for sexual intercourse. Virtually all men experience some erection failures at certain points in their lives. It can be the result of stress, depression, or sometimes even for no reason at all. For some, the problem becomes chronic. When it does, a diagnosis of ED is made. According to the American Foundation for Urologic Disease, it's a problem that affects about 18 million men in the U.S. alone.
As many other medicament drug Levetra has side effects. The main Levetras’s side effects are following:
Almost immediately after the discovery of cAMP by Sutherland and colleagues, cyclic nucleotide PDE activity was described (Butcher and Sutherland, 1962). With the subsequent discovery of cGMP, it was found that both cAMP and cGMP could be hydrolyzed by the same type of activity, i.e., hydrolysis of the 3? cyclic phosphate bond. On the basis of substrate competition studies, it was clear that at least some of these activities must have the same catalytic site. In fact, many of the early studies on cyclic nucleotides were directed toward understanding PDE activity since at that time it was much easier to measure PDE activity than either cAMP or cGMP themselves or the enzymes that catalyzed their synthesis. With the advent of assays using radioactive substrate, it became clear that there were likely to be multiple forms of PDEs with different kinetic and regulatory properties (Thompson et al., 1979; Beavo et al., 1982). However, it was not until higher resolution fractionation techniques, monoclonal antibodies, and molecular cloning and sequencing procedures were applied to the PDEs that the truly large number of different gene products was fully appreciated.
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